Von Willebrand's Disease
Von Willebrand’s Syndrome is a bleeding disorder of both animals and man.
The condition is caused by a deficiency in the amount of a certain protein required to help platelets (blood cells used for clotting blood) seal broken blood vessels.
Although many breeds can be affected, the Doberman Pinscher is the breed most commonly observed with the condition. Other breeds showing a high incidence are Chesapeake Bay Retrievers, Scotties, and Shelties.
Many dogs may be carriers of the condition even though not affected themselves.
Symptoms Of Von Willebrand's Disease:
Signs of the disease vary.
Many dogs having the condition never show clinical signs.
Others may hemorrhage from the nose, bladder, vagina, or mucous membranes.
Prolonged bleeding after surgery or injury is common.
If uncontrolled hemorrhage continues, it can result in death.
The time of life when initial signs are seen also varies. The condition may not be evident until 4 years of age in the Doberman Pinscher.
Diagnosis Of Von Willebrand's Disease:
Screening for the disease can be performed in the veterinary office with a blood sample if the disease is suspected.
Screening should be performed before breeding dogs within these breeds (especially Doberman Pinschers) to avoid passing this disease to their puppies.
Treatment Of Von Willebrand's Disease:
Blood transfusions may be needed to stabilize the acute case with active bleeding.
There is no curative treatment to prevent future problems.
Precautions for individuals with Von Willebrand's disease:
- Be sure to tell your veterinarian about past bleeding history. This is especially important if your dog requires a surgical procedure.
- Avoid medications that decrease clotting ability, such as aspirin.

